Dynamization A and B. One tube dose twice a week (for example Monday and Friday) in progressive order, from 1 to 8. The entire contents of the tube must be dissolved in the mouth in a single administration. It is preferable to take it in the evening before going to bed, on an empty stomach, so at least one hour after dinner; at the same time it is recommended not to use mint (toothpaste) or other strong flavors